Structural analysis ofPseudomonas aeruginosaH3-T6SS immunity proteins
نویسندگان
چکیده
منابع مشابه
Identification of T6SS-dependent effector and immunity proteins by Tn-seq in Vibrio cholerae.
Type VI protein secretion system (T6SS) is important for bacterial competition through contact-dependent killing of competitors. T6SS delivers effectors to neighboring cells and corresponding antagonistic proteins confer immunity against effectors that are delivered by sister cells. Although T6SS has been found in more than 100 gram-negative bacteria including many important human pathogens, fe...
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Protein secretion systems are critical to bacterial virulence and interactions with other organisms. The Type VI secretion system (T6SS) is found in many bacterial species and is used to target either eukaryotic cells or competitor bacteria. However, T6SS-secreted proteins have proven surprisingly elusive. Here, we identified two secreted substrates of the antibacterial T6SS from the opportunis...
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Type VI secretion systems (T6SS) function to deliver lethal payloads into target cells. Many studies have shown that protection against a single, lethal T6SS effector protein requires a cognate antidote immunity protein, both of which are often encoded together in a two-gene operon. The T6SS and an effector-immunity pair is sufficient for both killing and immunity. HereIn this paper we describe...
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ژورنال
عنوان ژورنال: FEBS Letters
سال: 2016
ISSN: 0014-5793
DOI: 10.1002/1873-3468.12291